Methylation & Precision Health Profile
This advanced methylation and nutrigenetic blood test provides insights into key biological pathways involved in nutrient metabolism, methylation processes, detoxification, neurotransmitter activity, and cellular function. Methylation is a naturally occurring biochemical process involved in many functions throughout the body, including DNA regulation, energy production, and the processing of nutrients and hormones.
The profile combines methylation pathway analysis with targeted nutrigenetic reporting to provide a broader overview of how genetic variations may influence nutritional requirements, exercise response, cognitive performance, and lifestyle-related traits. Genetic variants within pathways such as the folate cycle, methionine cycle, transsulphuration pathway, BH4 cycle, and urea cycle are reviewed as part of the analysis.
Results are presented alongside educational information and laboratory reference data where applicable to support a general understanding of methylation-related pathways and nutrigenetic factors. This test is intended for informational and wellness purposes only and is not designed to diagnose, treat, or prevent medical conditions. Results should always be interpreted in context and discussed with a qualified healthcare professional where appropriate.
What’s included
Advanced Methylation Pathway Analysis
Analysis of key pathways involved in methylation and nutrient metabolism, including the folate cycle, methionine cycle, transsulphuration pathway, BH4 cycle/neurotransmitter metabolism, and urea cycle.
Methylation Genes & SNPs
Review of selected genetic variations associated with methylation-related pathways, including genes commonly involved in nutrient conversion and biochemical processing.
Targeted Nutrigenetic Profile
Insights into genetic factors linked to vitamin and mineral metabolism, including vitamins A, B2, B6, B9, B12, C, D and E, as well as iron status, antioxidant pathways, omega-3 utilisation, and dietary sensitivities.
Food & Lifestyle Sensitivities
Includes analysis of genetic tendencies related to lactose and fructose tolerance, coeliac predisposition, salt sensitivity, caffeine metabolism, alcohol sensitivity, sugar preference, and bitter taste perception.
Detoxification Pathways
Assessment of genetic markers involved in detoxification and oxidative stress-related pathways.
Mental & Cognitive Wellness Insights
Includes traits associated with cognitive performance, stress response, neurotransmitter pathways, sleep quality, chronotype, and caffeine response.
Exercise & Recovery Genetics
Provides information related to power and endurance traits, aerobic training response, recovery efficiency, and injury predisposition.
Skin Health Reports
Insights into genetic markers associated with skin ageing, oxidative stress, pigmentation, glycation sensitivity, inflammation, and nickel sensitivity.
Who this test may be suitable for
This profile may be suitable for adults interested in learning more about methylation-related pathways, nutrigenetics, lifestyle factors, and general wellness traits. It may also be of interest to individuals exploring personalised nutrition, exercise response, or broader precision health insights.
This test is not intended to diagnose genetic conditions, nutritional deficiencies, or health disorders, and it should not replace professional medical advice, diagnosis, or treatment.
Deciding on which test to book
Before booking a blood test, it’s helpful to consider what information you would like to learn. Different tests measure different combinations of biomarkers, so reviewing what each test includes can help you choose the most appropriate option for you.
If you are unsure which test to book, you may find it useful to read the individual test descriptions or contact us for general guidance before making a booking. Once your test is booked, all required materials and preparations are arranged in advance to help ensure the process runs smoothly on the day.
Preparing for your blood test
Preparing for your blood test can help make sample collection easier and may reduce the chance of delays or the need for repeat sampling.
Staying calm and well hydrated is recommended. Drinking water beforehand may help improve blood flow and make sample collection more straightforward. Wearing loose or comfortable clothing can also help, particularly if you are attending a clinic appointment.
Some biomarkers may be influenced by factors such as food intake, exercise, alcohol, supplements, or the time of day. If any specific preparation steps are required for your test, these will be provided ahead of time. Where possible, it may be helpful to avoid strenuous exercise and heavy meals before your test unless advised otherwise.
If you are taking regular medication or supplements, you may wish to note this when reviewing your results. Do not stop taking prescribed medication unless advised to do so by a healthcare professional.
If you have any questions about preparation, feel unwell on the day of your test, or are unsure whether to proceed, please contact us before your appointment so we can provide further guidance.
On the day of your test
Allow yourself plenty of time and try to arrive feeling relaxed. Follow the instructions provided for sample collection carefully and ask for assistance if you are unsure at any stage.
After your sample has been collected, you will receive instructions on how to return it (for home tests) or what to expect next (for clinic-based tests). Results are issued once laboratory analysis is complete and are provided with reference ranges for context.
After your results
Results are supplied for informational purposes only and should be interpreted alongside your personal circumstances. If any results fall outside the reference range or raise questions, we recommend discussing them with a GP or qualified healthcare professional.
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